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CASPASE 12
Descriptors Found:
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DeCS
Descriptor
English
:
Caspase 12
Descriptor
Spanish
:
caspasa 12
Descriptor
Portuguese
:
Caspase 12
Synonyms
English
:
Caspase-12
Tree Number:
D08.811.277.656.262.500.126.550.920
D08.811.277.656.300.200.126.550.920
D12.644.360.075.405.550.920
D12.776.476.075.405.550.920
Definition
English
:
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region.
Caspase 12
is activated by pro-apoptotic factors that are released during cell stress and by
CARD SIGNALING ADAPTOR PROTEINS
. It activates
APOPTOSIS
by cleaving and activating
EFFECTOR CASPASES.
Entry Combination - descr/qualif
English
:
Caspase 12
/
antagonists & inhibitors
use
Caspase Inhibitors
History Note
English
:
2007(2000)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52230
Unique Identifier:
D053454
Occurrence in VHL
:
Similar:
DeCS